Biotechnology 4

Course Description

COURSE CONTENT

1. Biotechnological production of drugs (antibiotics and ergot alkaloids)
2. Importance of continuous development of new antibiotics
3. Alternative antimicrobial strategies
4. Fine chemicals – vitamins, hormones, products from plant cells and marine organisms
5. Viral vaccines and regulations in the field of biopharmaceuticals

LEARNING OUTCOMES

• analyse process parameters in the antibiotic production for the purpose of assessing the efficacy of the biotechnological process
• explain biotechnological production of vitamins, hormones and products from the marine organisms
• explain the development phases and procedures for the production of drugs for human use with an emphasis on viral vaccines
• explain the main phases of the biotechnological process of production, isolation and purification of antibiotics for the purpose of preparation of pharmaceutical preparations
• explain the specificity of animal cell biomass cultivation
• determine antibiotic concentration using microbiological methods for quantitatived determination of antibiotics and ELISA method
• determine bacterial susceptibility/resistance to antibiotics and to detect the r antibiotic resistance genes by PCR      
• describe the products from plant cell cultures
• prepare and sterilize cultivation media and to carry out the process of calf subcultivation
• outline the general scheme of the biotechnological process of antibiotic production

To enrol in this course, the following courses must be completed:

• Biotechnology 2
• Biochemistry 1
• Biochemistry 2
• Microbiology
• Transport Phenomena
• Unit Operations