Course Description
COURSE CONTENT
- Biotechnological production of drugs (antibiotics and ergot alkaloids)
- Importance of continuous development of new antibiotics
- Alternative antimicrobial strategies
- Fine chemicals – vitamins, hormones, products from plant cells and marine organisms
- Viral vaccines and regulations in the field of biopharmaceuticals
LEARNING OUTCOMES
- analyse process parameters in the antibiotic production for the purpose of assessing the efficacy of the biotechnological process
- explain biotechnological production of vitamins, hormones and products from the marine organisms
- explain the development phases and procedures for the production of drugs for human use with an emphasis on viral vaccines
- explain the main phases of the biotechnological process of production, isolation and purification of antibiotics for the purpose of preparation of pharmaceutical preparations
- explain the specificity of animal cell biomass cultivation
- determine antibiotic concentration using microbiological methods for quantitatived determination of antibiotics and ELISA method
- determine bacterial susceptibility/resistance to antibiotics and to detect the r antibiotic resistance genes by PCR
- describe the products from plant cell cultures
- prepare and sterilize cultivation media and to carry out the process of calf subcultivation
- outline the general scheme of the biotechnological process of antibiotic production
To enrol in this course, the following courses must be completed:
- Biotechnology 2
- Biochemistry 1
- Biochemistry 2
- Microbiology
- Transport Phenomena
- Unit Operations