Biotechnology 4

Course Coordinator

ECTS points:


Course number:

Course Description


  1. Biotechnological production of drugs (antibiotics and ergot alkaloids)
  2. Importance of continuous development of new antibiotics
  3. Alternative antimicrobial strategies
  4. Fine chemicals – vitamins, hormones, products from plant cells and marine organisms
  5. Viral vaccines and regulations in the field of biopharmaceuticals


  • analyse process parameters in the antibiotic production for the purpose of assessing the efficacy of the biotechnological process
  • explain biotechnological production of vitamins, hormones and products from the marine organisms
  • explain the development phases and procedures for the production of drugs for human use with an emphasis on viral vaccines
  • explain the main phases of the biotechnological process of production, isolation and purification of antibiotics for the purpose of preparation of pharmaceutical preparations
  • explain the specificity of animal cell biomass cultivation
  • determine antibiotic concentration using microbiological methods for quantitatived determination of antibiotics and ELISA method
  • determine bacterial susceptibility/resistance to antibiotics and to detect the r antibiotic resistance genes by PCR      
  • describe the products from plant cell cultures
  • prepare and sterilize cultivation media and to carry out the process of calf subcultivation
  • outline the general scheme of the biotechnological process of antibiotic production

To enrol in this course, the following courses must be completed:

  • Biotechnology 2
  • Biochemistry 1
  • Biochemistry 2
  • Microbiology
  • Transport Phenomena
  • Unit Operations
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