Genetics of Eukaryotes

Course Description

COURSE CONTENT

• Experimental organisms in research of genetics of eukaryota
• Characteristics, structure, function and maintenance of the eukaryotic genome
• Cell cycle regulation and tumorigeneses
• The genome and fundamentals of human genetics
• Fundamentals of population genetics

LEARNING OUTCOMES

• Propose a model organism for the implementation in a specific research and to state the characteristics of the organism that makes it suitable for carrying out that research
• Categorize individual genes based on their name and / or characteristics and predict the effects of mutation / inactivation of these genes as well asassociate the given phenotype with appropriate mutation
• Illustrate and explain different homologous recombination models
• Conclude and illustrate the result of homologous recombination between transforming DNA and yeast genome as well as intrachromosomal and interchromosomal homologous recombination
• Identify, categorize and compare similarities, differences and specifics in the structure, organization and expression of eukaryotic and prokaryotic genes and genomes
• Propose solutions on a problem questions based on the understanding of eukaryotic and population genetics
• Independently review and orally present the original scientific paper (written in English) from the field of genetics of eukaryota
• Perform simple genetic research on S.cerevisiae yeast, such as determining the frequency of "pop-out" recombination