Basics of Tissue Engineering

Course Coordinator

ECTS points:


Course number:

Course Description


Methodical units:

1. Definition and goals of TE & Cells and cellular environment in TE

  • L: General requirements and ethical aspects of TE in modern society
  • L: Cell selection and stem cell application in TE
  • L: Role and composition of extracellular matrix (ECM) and materials for ECM substitution

2. Principles of tissue and organ engineering

  • L: Cell diferentiaitiona and tissue vascularisation in TE
  • L: Design and preparation of 3D tissue scaffolds
  • L: Systems for controlled tissue/organ cultivation (TE bioreactors)

3. Tissue and organ engineering - case study

  • S: Tissue production in TE – Case study : cartiledge, bone, tendon
  • S: Organ production in TE– Case study: skin, bladder, heart valves, trachea


  • define origin and requirements of cells used in TE, as well as their growth and differentiation properties for tissues and organs design
  • distinguish the role of stem cells in tissue reparation
  • compare types, properties and fabrication procedures of natural and synthetic materials applied for cell immobilisation and tissue scaffold production
  • comment current restrictions and shortcomings in tissue engineering
  • compare achievements in the domain of tissue and organ engineering: skin, cartilage, bone, heart valves, etc.
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