Basics of Tissue Engineering

Course Description

COURSE CONTENT

Methodical units:

1. Definition and goals of TE & Cells and cellular environment in TE

• L: General requirements and ethical aspects of TE in modern society
• L: Cell selection and stem cell application in TE
• L: Role and composition of extracellular matrix (ECM) and materials for ECM substitution

2. Principles of tissue and organ engineering

• L: Cell diferentiaitiona and tissue vascularisation in TE
• L: Design and preparation of 3D tissue scaffolds
• L: Systems for controlled tissue/organ cultivation (TE bioreactors)

3. Tissue and organ engineering - case study

• S: Tissue production in TE – Case study : cartiledge, bone, tendon
• S: Organ production in TE– Case study: skin, bladder, heart valves, trachea

LEARNING OUTCOMES

• define origin and requirements of cells used in TE, as well as their growth and differentiation properties for tissues and organs design
• distinguish the role of stem cells in tissue reparation
• compare types, properties and fabrication procedures of natural and synthetic materials applied for cell immobilisation and tissue scaffold production
• comment current restrictions and shortcomings in tissue engineering
• compare achievements in the domain of tissue and organ engineering: skin, cartilage, bone, heart valves, etc.