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Program: preddiplomski
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Course number:
39785 (PDBT) i 53713 (DBPI)
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Course Description
COURSE CONTENT
- Vitamins - definition, classification, nomenclature, chemical composition and role in the organism.
- Water soluble vitamins-B-vitamins, vitamin C. Structure, properties and industrial production.
- Fat soluble vitamins- vitamins A,D, E i K. Stucture, properties and industrial production
- Mass balance, quantification and yield of vitamine sinthesys process (from raw material to product)
- Hormones - definition, classification, nomenclature, chemical composition and role in the organism
- Steroid hormones- androgens, estrogens, progestogens and corticosteroids. Raw materials and production. Derivates of steroid hormones and application as anabolics.
- Polipeptide hormones. Insulin. Insulin production by E. coli i S. cerevisiae. Growth hormone and production-isolation from natural sources and rDNA process by E. coli.
- Erythropoietin-production. Gonadotropic hormones and production. Purification processes of rDNA hormones.
- Plant hormones-role, chemical composition and role in plants.
- Application of anabolics in humans and animals-specific examples
- Production of GM plants with increase vitamine content
- r Growth hormone in milk production
LEARNING OUTCOMES
- define the role of vitamins and hormones in organism
- compare chemical and biotechnological processes of vitamine production
- explain and compare processes of steroid and peptide hormones
- discuss new areas of vitamines and hormones application (rDNA technology)
- calculate the mass balance and yield during the synthesis, isolation and quantitative determination of vitamins and hormones
To enrol in this course, the following courses must be completed (undergraduate studies):
- Biotechnology 2
- Biochemistry 1
- Biochemistry 2
- Microbiology
- Transport Phenomena
- Unit Operations