Course Description
COURSE CONTENT
Methodical units:
1. Definition and goals of TE & Cells and cellular environment in TE
- L: General requirements and ethical aspects of TE in modern society
- L: Cell selection and stem cell application in TE
- L: Role and composition of extracellular matrix (ECM) and materials for ECM substitution
2. Principles of tissue and organ engineering
- L: Cell diferentiaitiona and tissue vascularisation in TE
- L: Design and preparation of 3D tissue scaffolds
- L: Systems for controlled tissue/organ cultivation (TE bioreactors)
3. Tissue and organ engineering - case study
- S: Tissue production in TE – Case study : cartiledge, bone, tendon
- S: Organ production in TE– Case study: skin, bladder, heart valves, trachea
LEARNING OUTCOMES
- define origin and requirements of cells used in TE, as well as their growth and differentiation properties for tissues and organs design
- distinguish the role of stem cells in tissue reparation
- compare types, properties and fabrication procedures of natural and synthetic materials applied for cell immobilisation and tissue scaffold production
- comment current restrictions and shortcomings in tissue engineering
- compare achievements in the domain of tissue and organ engineering: skin, cartilage, bone, heart valves, etc.