Technology of Vitamin and Hormone Production

Course Description

COURSE CONTENT

• Vitamins - definition, classification, nomenclature, chemical composition and role in the organism.
• Water soluble vitamins-B-vitamins, vitamin C. Structure, properties  and industrial production.
• Fat soluble vitamins- vitamins A,D, E i K. Stucture, properties and industrial production
• Mass balance, quantification and yield of vitamine sinthesys process (from raw material to product)
• Hormones - definition, classification, nomenclature, chemical composition and role in the organism
• Steroid hormones- androgens, estrogens, progestogens and corticosteroids. Raw materials and production. Derivates of steroid hormones and application as anabolics.
• Polipeptide hormones. Insulin. Insulin production by E. coli i S. cerevisiae. Growth hormone and production-isolation from natural sources and rDNA process by E. coli.
• Erythropoietin-production. Gonadotropic hormones and production. Purification processes of rDNA hormones.
• Plant hormones-role, chemical composition and role in plants.
• Application of anabolics in humans and animals-specific examples
• Production of GM plants with increase vitamine content
• r Growth hormone in milk production

LEARNING OUTCOMES

• define the role of vitamins and hormones in organism
• compare chemical and biotechnological processes of vitamine production
• explain and compare processes of steroid and peptide hormones
• discuss new areas of vitamines and hormones application (rDNA technology)
• calculate the mass balance and yield during the synthesis, isolation and quantitative determination of vitamins and hormones

To enrol in this course, the following courses must be completed (undergraduate studies):

• Biotechnology 2
• Biochemistry 1
• Biochemistry 2
• Microbiology
• Transport Phenomena
• Unit Operations