Biochemical EngIneering

Course Coordinator

ECTS points:
8

Program:
preddiplomski

Course number:
39803

COURSE CONTENT

Definition, importance and range of biochemical engineering and its development directions
Bioreactor systems for biotechnological production
Bioprocess conduction manners – batch and fed batch process
Bioprocess conduction manners – semi-continuous and continuous process
Mixing and aeration in bioprocesses
Monitoring, control and regulation of bioprocesses
Sterilisation of equipment, media and air for biotechnological production
Application of mathematical models in biotechnological production
Immobilised biocatalytic systems
Separation and purification of biotechnological products

LEARNING OUTCOMES

prepare cultivation media and inoculum for different bioprocess conduction manners (batch, fed batch, semi-continuous and continuous)
establish and solve mass balance and quantify bioprocess kinetics for different bioprocess conduction manners
establish and manage different bioprocess conduction manners
calculate bioprocess efficiency parameters for different bioprocess conduction manners
propose adequate equipment for bioprocess conduction on semi-solid and solid substrate as well as on liquid cultivation media
create and build up optimal system for monitoring and control of bioprocesses
calculate, establish and manage of batch and continuous sterilization of cultivation media as well as air sterilization
develop and use mathematical models for bioprocess control and optimization
propose and create systems for bioprocess conduction with immobilized biocatalysts of first and second generation
propose adequate process for microbial biomass separation, microbial cells disruption and separation of microbial metabolism products
create and build up optimal technological line for bioprocess conduction in industrial scale

To enrol in this course, the following courses must be completed: