Measurement and Process Control

Course Description

COURSE CONTENT

• Introduction to the course; Basic features of measurement and control of biotechnological processes
• Basics of measurement, metrology; calibration; traceability; measurement errors, legal regulations
• Introduction to process measurements
• Measuring Transmitters - Selection and General Features
• Measurement of Physics variables in the BT process - level, flow, pressure, temperature
• Measurements for bioreactor control (optical density, respiration ratio, dissolved oxygen, CO2, ...).
• Automatic FIA measurement systems
• Process automatization, process control, biotechnological processes control
• The Dynamics of  1st Order System
• Parameter regulation in BT process - examples - level, pH, turbidimeter)
• The Dynamics of 2nd Order System
• Application of artificial intelligence algorithms for monitoring and control of biotechnological processes.

LEARNING OUTCOMES

• interpret the basic concepts of measurement systems for computer control of processes
• calculate measurement errors and calibration parameters.
• apply chemometric methods for control of biotechnological processes
• choose the appropriate interfaces to connect the computer with measurement instrumentation in BT process
• analyze linearity of the system using the transfer functions of basic technological operations in biotechnology.
• analyze the stability of process control
• formatting PID controller parameters for higher-level system models with time delay.

To enrol in this course, the following courses must be completed:

• Transport Phenomena
• Unit Operations
• Numerical Methods and Programming
• Statistics