The Fundamentals of Bioorganometallic Chemistry

Code:

53267

ECTS:

2.0

Lecturers in charge:

prof. dr. sc. Lidija Barišić

Lecturers:

izv. prof. dr. sc. Veronika Kovač - Laboratory exercises

Take exam:

Studomat

Load:

1. komponenta

Lecture type	Total
Lectures	15
Laboratory exercises	23

* Load is given in academic hour (1 academic hour = 45 minutes)

Description:

Bioorganometallic chemistry investigates biologically active complexes in which classical organometallic ligands and biomolecules are linked by carbon metal bonds. Bioconjugates of organometallic compounds and biomolecules (DNA, carbohydrates, steroids, amino acids, peptides) are used in cancer and infectious disease therapy, immunoassays, molecular recognition, enzyme catalysis and toxicology. The aim of this course is to familiarise students with the possibilities of using bioorganometallic compounds in pharmacology and biotechnology, with a focus on bioorganometallic complexes of particular biological and medical importance.

Learning outcomes:

Literature:

1. G. Jaouen (Editor), Bioorganometallics: Biomolecules, Labeling, Medicine, John Wiley & Sons,
Weinheim, 2006.
2. G. Simonneaux (Editor), Bioorganometallic Chemistry (Topics in Organometallic Chemistry),
Springer-Verlag Berlin Heidelberg, 2006.
3. P. Štepnička (Editor), Ferrocenes: Ligands, Materials and Biomolecules, John Wiley & Sons,
Chichester, 2008.
4. D. R. van Staveren, N. Metzler-Nolte, Bioorganometallic Chemistry of Ferrocene, Chem. Rev. 104
(2004) 5931-5985.
5. E. A. Hillard, G. Jaouen, Bioorganometallics: Future Trends in Drug Discovery, Analytical Chemistry
and Catalysis, Organometallics 30 (2011) 20-27.
6. G. Jaouen and M. Salmain (Editors), Bioorganometallic Chemistry. Applications in Drug Discovery,
Biocatalysis, and Imaging, Wiley-VCH Verlag GmbH & Co. KGaA, Boschstr. 12, 69469 Weinheim,
Germany, 2015.,

1. semester

Molekularna biotehnologija - A1 - Regular studij - Molecular Biotechnology

3. semester

Molekularna biotehnologija - A1 - Regular studij - Molecular Biotechnology

Consultations schedule:

The Fundamentals of Bioorganometallic Chemistry