prof. dr. sc. Ivan-Krešimir Svetec
Laboratorij za biologiju i genetiku mikroorganizama
Radno mjesto:
redoviti profesor u trajnom izboru
Funkcija:
Voditelj studija
Zavod / Katedra:
Laboratorij za biologiju i genetiku mikroorganizama
Godina diplomiranja:
1995.
Godina magistriranja:
2000.
Godina doktoriranja:
2005.
Na sveučilištu od:
1994.
Lokacija:
Kršnjavoga 25
Telefon:
+ 385 1 4836 016
E-mail:
E-mail
Nastava
Prijediplomski
- Genetičko inženjerstvo (39804) — Nositelj, Laboratorijske vježbe
- Genetičko inženjerstvo (269681) — Nositelj
- Genetičko inženjerstvo (predmet na engleskom jeziku) (191414) — Nositelj, Nositelj
- Genetika eukariota (predmet na engleskom jeziku) (210378) — Nositelj, Seminar, Nositelj, Seminar
- GMO u proizvodnji hrane (predmet na engleskom jeziku) (192026) — Nositelj, Seminar, Nositelj, Seminar
- Molekularna genetika (32425) — Nositelj
- Molekularna genetika (252777) — Nositelj
- Praksa i završni rad (39867) — Laboratorijske vježbe
- Završni rad (269684) — Laboratorijske vježbe
Diplomski
- Eksperimentalni pristup u molekularno-genetičkim istraživanjima (270453) — Nositelj, Seminar
- Genetičko inženjerstvo (razlikovni predmet) (120303) — Nositelj
- Genetika eukariota (53250) — Nositelj, Seminar
- Molekularna genetika (razlikovni predmet) (70462) — Nositelj
- GMO u proizvodnji hrane (53261) — Predavanja, Seminar
- Suvremene metode u analitici hrane (53704) — Predavanja, Laboratorijske vježbe
- Suvremene metode u kontroli kvalitete hrane (53287) — Predavanja, Laboratorijske vježbe
- Suvremene metode u kontroli kvalitete hrane (239536) — Predavanja, Laboratorijske vježbe
- Uvod u diplomski rad (66880) — Seminar
- Diplomski rad (66881) — Laboratorijske vježbe
Doktorski
- Mikrobna genetika i genetičko inženjerstvo (165665) — Nositelj, Seminar
Specijalistički
Znanstvene publikacije
-
Palindrome-induced recombination in S. cerevisiae depends on sequence length and spacer size
(2025)
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THE ROLE OF RAD27 IN THE STABILITY OF LARGE PALINDROMIC SEQUENCES IN THE EUCARYOTIC GENOME
Book of Abstracts of 9th Faculty of Science PhD Student Symposium,Sveučilište u Zagrebu Prirodoslovno-matematički fakultet, (2025) str. 92-92
-
Production of Lactate by Metabolically Engineered Scheffersomyces stipitis
Journal of fungi, 11 (2025) str. 413-428, doi: 10.3390/jof11060413
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GENETIC MODIFICATION OF NONCONVENTIONAL YEAST Scheffersomyces stipitis FOR LACTATE PRODUCTION
Natural Resources Green Technology and Sustainable Development 5 (2024): Book of Abstracts,University of Zagreb, Faculty of Food Technology and Biotechnology, (2024) str. 110-110
-
Analiza transformanata kvasca Scheffersomyces stipitis metodom hibridizacije DNA po Southernu
(2023)
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Uporaba lančane reakcije polimerazom u sintezi fragmenta DNA za inaktivaciju kvaščevog gena YKU70
(2022)
-
Transformacija bakterije Escherichia coli plazmidima pUC-GW-RadH i pUC-GW-NoxV
(2022)
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PALINDROME-INITAITED GENOME INSTABILITY IN EUKARYOTIC CELLS
HDBMB22 From Science to Knowledge, (2022) str. 139-139
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Genetic transformation of non-conventional yeasts belonging to the Schwanniomyces genus
(2022)
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Toolbox for Genetic Transformation of Non-Conventional Saccharomycotina Yeasts: High Efficiency Transformation of Yeasts Belonging to the Schwanniomyces Genus
Journal of fungi, 8 (2022) str. 531-537, doi: 10.3390/jof8050531
-
Gene targeting efficiency in non-conventional yeasts
FEMS Conference on Microbiology 2022, (2022) str. 79-79
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SARS-Cov2 S Protein Features Potential Estrogen Binding Site
Food technology and biotechnology, 59 (2021) str. 1-7, doi: 10.17113/ftb.59.01.21.6820
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Palindromes in DNA—A Risk for Genome Stability and Implications in Cancer
International Journal of Molecular Sciences,International journal of molecular sciences, 22 (2021) 2840, 18, doi: 10.3390/ijms22062840
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Supersaturated-oxygen aeration effects on a high-loaded membrane bioreactor (HL-MBR): Biological performance and microbial population dynamics
Science of the Total Environment,Science of the total environment, 771 (2021) 144847, 12, doi: 10.1016/j.scitotenv.2020.144847
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Bioactivity comparison of electrospun PCL mats and liver extracellular matrix as scaffolds for HepG2 cells
Polymers, 13 (2021) 279, 11, doi: 10.3390/polym13020279
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Određivanje uspješnosti genskog ciljanja u kvascu Kluyveromyces marxianus
(2020)
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Lactic acid bacteria isolated from equid milk and their extracellular metabolites show great probiotic properties and anti-inflammatory potential
International dairy journal, 112 (2020) 104828, 8, doi: 10.1016/j.idairyj.2020.104828
-
Priprema biokatalizatora
Knjiga sažetaka XIII. Susret mladih kemijskih inženjera,Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), (2020) str. 38-38
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Metabolically engineered Lactobacillus gasseri JCM 1131 as a novel producer of optically pure L‑ and D‑lactate
World journal of microbiology & biotechnology, 36 (2020) 111, 16, doi: 10.1007/s11274-020-02887-2
-
Size-dependent antirecombinogenic effect of short spacers on palindrome recombinogenicity
DNA Repair,DNA repair, 90 (2020) 102848, 8, doi: 10.1016/j.dnarep.2020.102848
-
Restrikcijska analiza plazmida pRS40cN, pRS52cN, pRS53cN i pRS55cN
(2020)
-
Metode genetičke transformacije kvasaca
(2020)
-
Metoda slučajnog umnažanja polimorfne DNA (RAPD)
(2020)
-
Efficient transformation procedure for yeasts belonging to the Schwanniomyces genus
FEMS Online Conference on Microbiology, (2020) str. 140-140
-
Gene targeting in yeasts – fun and easy (or not?!)
10th Central European Genome Stability and Dynamics Meeting, (2019)
-
Recombinogenicity of palindromic sequences in yeast.
(2019)
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Palindromic DNA sequences present a risk for the stability of eukayotic genome
Power of Microbes in industry and environment,, (2019) str. 107-107
-
Novel Approach in the Construction of Bioethanol- Producing Saccharomyces cerevisiae Hybrids
Food technology and biotechnology, 57 (2019) str. 5-16, doi: 10.17113/ftb.57.01.19.5685
-
Sgs1 and Exo1 suppress targeted chromosome duplication during gene targeting
Book of Abstracts of 47th EEMGS Meeting, (2019) str. 70-70
-
Genetička transformacija kvasaca iz roda Schwanniomyces
(2019)
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Kloniranje dijela genoma bakteriofaga lambda u plazmide pRS40 coKanR, pRS40 coHyrR i pRS40 coNrsR
(2019)
-
Detection and characterization of trim mobile elements in bivalve SPECIES Cerastoderma edule and Glycymeris glycymeris
(2019)
-
Recombinogenicity of perfect palindromes and quasipalindromes with short central spacers in vivo
4th Congress of Croatian Geneticists with International Participation Book of Abstracts,Hrvatsko genetičko društvo, (2018) str. 26-26
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Usporedba rasta bakterije Lactobacillus amylovorus na novodizajniranoj (sMRS) i standardnoj (MRS) podlozi
(2018)
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Overexpression of YAP1 gene increases the resistance of yeast strains to inhibitors found in lignocellulosic hydrolysates
4th Congress of Croatian Geneticists with International Participation Book of Abstracts,Hrvatsko genetičko društvo, (2018) str. 66-66
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Compatibility of ten frequently used fluorescent proteins with the EVOS Floid microscope
4th Congress of Croatian Geneticists with International Participation Book of Abstracts,Hrvatsko genetičko društvo, (2018) str. 64-64
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Rezistencija transformiranih sojeva kvasca s pojačanom ekspresijom odabranih gena na inhibitore rasta
(2018)
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Novel approach in developing Saccharomyces cerevisiae hybrid bioethanol producers by mating of natural isolates having desirable traits
Journal of Biotechnology, Volume 280, Supplement,Thomson Digital, (2018) str. S89-S89, doi: 10.1016/j.jbiotec.2018.06.294
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Genetičko inženjerstvo, kvasac i alternativna goriva
Priroda 03/04 ; 36-39, (2017)
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Construction of novel Saccharomyces cerevisiae hybrid strains resistant to growth and fermentation inhibitors
Journal of Biotechnology, Special Issue, (2017) str. 15-15, doi: 10.1016/j.jbiotec.2017.06.054
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In Saccharomyces cerevisiae gene targeting fidelity depends on a transformation method and proportion of the overall length of the transforming and targeted DNA.
Fems yeast research,FEMS yeast research, 17 (2017) fox041, 10, doi: 10.1093/femsyr/fox041
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Analysing targeted chromosome duplication in yeast Saccharomyces cerevisiae by qPCR
Acta Microbiologica et Immunologica Hungarica,Acta microbiologica et immunologica Hungarica, (2017) str. 170-171
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Transformation and genetic recombination in yeast Dekkera bruxellensis
(2017)
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Brettanomyces bruxellensis: Development of genetic transformation system
Journal of Biotechnology Special issue, (2017) str. 16-16, doi: 10.1016/j.jbiotec.2017.06.057
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Kompatibilnost deset često korištenih fluorescentnih proteina s mikroskopom EVOS Floid
(2017)
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POJAČANA EKSPRESIJA ODABRANIH GENA I REZISTENCIJA KVASCA Saccharomyces cerevisiae NA INHIBITORE RASTA
(2016)
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Transformation of yeast Saccharomyces cerevisiae with plasmid containing growth inhibitor resistance gene YAP1
(2016)
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Construction of novel Saccharomyces cerevisiae hybrid diploids for bioethanol production
6th Conference on Physiology of Yeasts and Filamentous Fungi,-, (2016)
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Development of molecular-genetic tools for yeast Dekkera/Brettanomyces bruxellensis
6th Conference on Physiology of Yeasts and Filamentous Fungi, (2016)
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Construction of Saccharomyces cerevisiae hybrid diploids for bioethanol production
EBTNA 2016, (2016)
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Construction of yeast strains - fun and easy?!
Power of microbes in industry and environment 2016, (2016)
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Genome assembly of lactic acid bacteria: the case of Lactobacillus amylovorus DSM 220531T
Abstracts of European Biotechnology Conference held in Latvia during 05–07 May 2016,Elsevier, (2016)
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KONTRUKCIJA I ODREĐIVANJE OSJETLJIVOSTI HIBRIDNIH SOJEVA KVASCA Saccharomyces cerevisiae NA INHIBITORE RASTA
(2015)
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Rekombinogenost palindroma i kvazipalindroma u genomu kvasca Saccharomyces cerevisiae
(2015)
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Improved electroporation procedure for genetic transformation of Dekkera/Brettanomyces bruxellensis
Fems yeast research,FEMS yeast research, 15 (2015) str. fov096-1-fov096-5, doi: 10.1093/femsyr/fov096
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Bioinformatic analysis of carbon utilization pathways in Lactobacillus amylovorus strains
Journal of Biotechnology,Journal of biotechnology, Elsevier, (2015) str. S45-S45
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Bioinformatic analysis of carbon utilization pathways in Lactobacillus amylovorus strains
Journal of Biotechnology,Journal of biotechnology, Elsevier, (2015)
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Kloniranje gena ATR1, FLR1, GSH1 i YAP1 iz kvasca Saccharomyces cerevisiae soj UWOPS87- 2421 u bakteriji Escherichia coli
(2015)
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SINTEZA I ODREĐIVANJE OSJETLJIVOSTI DIGOKSIGENINOM OBILJEŽENE PROBE ZA HIBRIDIZACIJU DNA METODOM PO SOUTHERN-U
(2014)
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Sgs1 and Exo1 suppress targeted chromosome duplication during ends-in and ends-out gene targeting
DNA repair, 22 (2014) str. 12-23, doi: 10.1016/j.dnarep.2014.07.004
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Colour-based screening for detection of genes affecting palindrome stability in vivo
(2013)
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Genetic side-effects during gene replacement in yeast Saccharomyces cerevisiae
(2013)
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Genetic transformation of yeast Dekkera/Brettanomyces bruxellensis
(2013)
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Genetic transformation and characterization of yeast Dekkera/Brettanomyces bruxellensis
(2013)
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Utjecaj iskorištenosti hranjive podloge na konstitutivni SOS odgovor u rekombinacijskim mutantima bakterije Escherichia coli
(2013)
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Sinteza fragmenata DNA za inaktivaciju gena RAD27 lančanom reakcijom polimerazom
(2013)
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Genetic transformation of the yeast Dekkera/Brettanomyces bruxellensis with non-homologous DNA
Journal of microbiology and biotechnology, 23 (2013) str. 674-680, doi: 10.4014/jmb.1211.11047
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Genetic Transformation of the Yeast Dekkera/Brettanomyces bruxellensis with Non- Homologous DNA
Journal of microbiology and biotechnology, 23 (2013) str. 674-680
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Konstrukcija mutanta SLX4 kvasca Saccharomyces cerevisiae
(2012)
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Generiranje dugačkih palindroma u genu ADE2 pomoću programa Synonymous Codon Shuffler
(2012)
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Molekularna karakterizacija neočekivanih genetičkih događaja nastalih tijekom zamjene gena u kvascu
(2012)
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Konstrukcija plazmida pDUK
(2012)
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Rekombinogenost pseudopalindroma u genomu kvasca Saccaromyces cerevisiae
(2012)
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A pioneer of yeast genetics in Croatia : Zoran Zgaga’s contribution to make national research acknowledged worldwide
Periodicum biologorum, 114 (2012) str. 1-14
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Konstrukcija i provjera plazmida pAB9-126S8
(2012)
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Sgs1 protein prevents break-induced replication during gene targeting in yeast Saccharomyces cerevisiae
(2012)
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Genetic instability of closely spaced invarted repeats in the genome of Saccharomyces cerevisiae
(2012)
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Eskperimentali sustav za dentifikaciju proteina uključenih u nestabilnost palindroma u DNA
(2012)
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Intragenic synonymous codon shuffling as a tool for studying palindrome abundance in protein coding genes
(2012)
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Palindromes – dangerous secondary structures in DNA
(2011)
-
Candida utilis kao urzočnik kandidmije u novorođenčadi
Knjiga sažetaka , 9.hrvatski konges kliničke mikrobiologije s međunarodnim sudjelovanjem, (2011)
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Utjecaj bakra na rast haploidnih i diploidnih sojeva kvasca Saccharomyces cerevisiae
(2011)
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Indukcija duplikacije kromosoma u kvasca Saccharomyces cerevisiae
(2011)
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ZASTUPLJENOST PALINDROMA U KODIRAJUĆOJ DNA KVASCA Saccharomyces cerevisiae
(2011)
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Dissecting RNA Polymerase II transcription termination complex in Saccharomyces cerevisiae using a dosage-suppressor assay as a tool
(2011)
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Yeast pathology - a systemic analysis of death and aging in budding yeast
(2011)
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Recombinogenicity and Distribution of Palindromes in the Yeast Saccharomyces cerevisiae Genome
(2011)
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Candida utilis candidaemia in neonatal patients
Journal of Medical Microbiology, 60 (2011) str. 838-841, doi: 10.1099/jmm.0.023408-0
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Identification and characterization of potential autochthonous starter cultures from Croatian "brand" product "Slavonski kulen"
Meat science, 88 (2011) str. 517-524, doi: 10.1016/j.meatsci.2011.02.003
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Sgs1 controls the fidelity of gene targeting
(2011)
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Neonatal Candida utilis candidemia and colonization : analysis of in vitro antifungal susceptibilities and molecular typing of causative isolates
5th Trends in Medical Mycology : abstracts ; u: Mycoses 54 (2011) (S2) 1–189 ; Posters S6-S181,Mycoses, (2011) str. 126-127
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PRIMJENA PROTEINA Abf2 I MC1 U PRIPREMI KRATKE KRUŽNE DNA ZA TRANSFEKCIJU STANICA U KULTURI
(2010)
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Kvasci u biotehnološkoj proizvodnji
Plejada, (2010)
-
Physical and genetic parameters affecting palindrome-stimulated intrachromosomal recombination in Saccharomyces cerevisiae
Power of Microbes in Industry and Environment 2010,Hrvatsko mikrobiološko društvo, (2010) str. 102-102
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Genetika kvasca i primjena genetičkih istraživanja u oplemenjivanju industrijskih sojeva kvasca
Kvasci u biotehnološkoj proizvodnji,Plejada, (2010) str. 39-68
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Restrikcijska analiza ekspresijskog plazmida za enzim I-SceI
(2010)
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Restrikcijska analiza ekspresijskog plazmida za enzim I-SceI
(2010)
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Transformation associated chromosome duplication and Essentiality of essential genes
(2010)
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Transformation associated chromosome duplication and essentiality of essential genes.
(2010)
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Synbiotic effect of Lactobacillus helveticus M92 and prebiotics on the intestinal microflora and immune system of mice
Journal of Dairy Research,Journal of dairy research, 76 (2009) str. 98-104
-
The efficiency of gene replacement in yeast is allele-specific
EMBO Young Scientist Forum, (2009)
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Size-dependent palindrome-induced intrachromosomal recombination in yeast
DNA repair, 8 (2009) str. 383-389, doi: 10.1016/j.dnarep.2008.11.017
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Duplikacija kromosoma kao posljedica pop-out rekombinacije
(2009)
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IZLUČIVANJE HETEROLOGNO EKSPRIMIRANIH PROTEINA U KVASCA Pichia pastoris POMOĆU SEKVENCIJE α-MF
(2009)
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TRANSFORMACIJA I KARAKTERIZACIJA KVASCA Dekkera bruxellensis
(2009)
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Uloga "pop-out" rekombinacije u evoluciji genoma kvasca Saccharomyces cerevisiae
(2009)
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Lactobacillus helveticus M92 and prebiotic substrates: synbiotic effect on the intestinal microflora of mice and their immune system
(2008)
-
Genetic duplications as a side-effect of targeted gene replacement in yeast
Enviromental mutagens and human health, (2008) str. 170-170
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A critical size for palindrome induced intrachromosomal recombination in yeast
Environmental mutagens and human health, (2008) str. 189-189
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Izrada krivulje preživljenja kvasca Dekkera bruxellensis nakon zračenja ultraljubičastim svjetlom
(2008)
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Genotipizacija kvasca Dekkera bruxellensis pomoću RAPD metode
(2008)
-
Recombinogenic potential of palindromic sequences is determined by their size and position in the yeast genome
50 Years of Molecular Biology in Croatia,Institut Ruđer Bošković, (2008) str. 14-14
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Targeted chromosome duplication as a side-efect of gene targeting in yeast
50 Years of Molecular Biology in Croatia,Institut Ruđer Bošković, (2008) str. 58-58
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Eksperimentalni sustavi: Kvasac Saccharomyces cerevisiae
Metode u molekularnoj biologiji,Institut Ruđer Bošković, (2007) str. 23-35
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Genetic duplications as a side-effect of gene replacement in yeast
ESF-EMBO Symposium on Comparative Genomics of Eukaryotic Microorganisms: Eukaryotic Genome Evolution, (2007)
-
Ends-out recombination as a source of genetic duplications in Yeast
Book of abstracts of Central European Symposium on Industrial Microbiology and Microbial Ecology, (2007) str. 26-26
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Genetic side effects accompanying gene targeting in yeast: the influence of short heterologous termini
Yeast, 24 (2007) str. 637-652, doi: 10.1002/yea.1497
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Filamentozni bakteriofagi
Metode u molekularnoj biologiji,Institut Ruđer Bošković, (2007) str. 19-22
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Odabrane metode rada s mikroorganzmima: Kvasac Saccharomyces cerevisiae
Metode u molekularnoj biologiji,Institut Ruđer Bošković, (2007) str. 936-948
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Mutageneza in vitro po Kunkelu
Metode u molekularnoj bilogiji,Institut Ruđer Bošković, (2007) str. 447-449
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Izdvajanje plazmida (fagmida) u jednolančanom obliku pomoću filamentoznog bakteriofaga
Metode u molekularnoj biologiji,Institut Ruđer Bošković, (2007) str. 150-152
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Transformacija pomoću litijevog acetata
Metode u molekularnoj biologiji,Institut Ruđer Bošković, (2007) str. 937-939
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Synbiotic effect of Lactobacillus acidophilus M92 and prebiotic substrates on the intestinal microflora of mice and their immune system
Power of microbes in industry and environment 2007,Pressum, (2007) str. 75-75
-
Palindromes in prokaryotic genomes
Book of abstracts of The Congress of the Croatian Society of Biochemistry and Molecular Biology on the occasion of the 30th Anniversary, (2006) str. 60-60
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Importance of S-layer proteins in probiotic activity of Lactobacillus acidophilus M92
Journal of Applied Microbiology,Journal of applied microbiology, 2 (2005)
-
Palindrome content of the yeast Saccharomyces cerevisiae genome
Current genetics, 47 (2005)
-
Palindromic sequences in the Saccharomyces cerevisae genome
Book Of Abstracts Of The Second Congress Of Croatian Geneticists, (2005) str. 41-41
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Inactivation of the SGS1 and EXO1 genes synergistically stimulates the efficiencies of yeast transformation
Book Of Abstracts Of The Second Congress Of Croatian Geneticists, (2005) str. 87-87
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Utjecaj palindroma na homolognu rekombinaciju i stabilnost kvašćevog genoma
(2005)
-
Inactivation of the SGS1 and EXO1 genes sinergistically stimulates plasmid integration in yeast
Food technology and biotechnology, 43 (2005)
-
Functional role of S-layer proteins in probiotic strain Lactobacillus acidophilus M92
2nd Central European Meeting and 5th Croatian Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts,EURO-V.A.L.d.o.o., (2004)
-
Size-dependent palindrome-induced intrachromosomal recombination in yeast
Cinquieme Colloque des Replicatio, Recombinaison, Reparation, (2003)
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Palindromes: required but risky
EMBO Lecture Course on New Developments in Genomics for Biomedicine,Institut "Jožef Štefan", Ljubljana, (2003)
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Palindromes as inducers of mitotic recombination in yeast
First Croatian Congress on Molecular Biosciences : Book of Abstracts,Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, (2002) str. 65-65
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Plasmid integration in yeast : conceptions and misconceptions
Current Studies of Biotechnology. Volume II : Environment,Hrvatsko Društvo za Biotehnologiju, (2001) str. 135-142
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The influence of a palindromic insertion on plasmid integration in yeast
Food technology and biotechnology, 39 (2001) str. 169-173
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Utjecaj kratkih heterolognih sekvencija na integraciju plazmida u genom kvasca Saccharomyces cerevisiae
(2000)
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Influence of homology size and polymorphysm on plasmid integration in the yeast CYC1 DNA region
Current genetics, 37 (2000) str. 292-297, doi: 10.1007/s002940050530
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The influence of homology polymorphism and length on plasmid integration in yeast
Abstracts of the XIX International Conference on Yeast Genetics and Molecular Biology ; u: Current Genetics 35 (1999) (3/4) ; 08-Recombination and repair ; 347-365,Current genetics, Springer, (1999) str. 365-365
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Plasmid integration is preferred in the C-terminal part of the yeast ura3 gene
(1998)
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The influence of heterologous insertions on homologous recombination in Saccharomyces cerevisiae
3. Hrvatski kongres prehrambenih tehnologa, biotehnologa i nutricionista : knjiga sažetaka,Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, (1998) str. 107-108
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Plasmid integration is preferred in the C-terminal part of the yeast ura3 gene
Abstracts of the First Congress of Croatian Geneticists with International Participation ; u: Periodicum biologorum 100 (1998) (S1),Periodicum biologorum, Hrvatsko prirodoslovno društvo, (1998) str. 39-40
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Yeast transformation and horisontal gene transfer
18th ISSY - Yeast Nutrition and Natural Habitats - Book of Abstracts,Slovene Microbiological Soc.; International Comission for Yeasts, (1997)